个人主页
袁宗辉
  • 专业技术职务:教授
  • 部     门:动科动医学院
  • 联系电话:
  • 电子邮箱:
  • 研究方向:

个人简介 收起

袁宗辉,男,1958年2月生,教授,博士生导师,华中农业大学二级岗教授。1978.03.-1981.12. 华中农业大学兽医专业本科生。1982.01.-1984.12. 华中农业大学兽医药理学及毒理学硕士生。1985.01.-1987.12. 华南农业大学兽医药理学及毒理学博士生。我国第一个兽医药理学及毒理学博士。1988.01.-1993.05. 华南农业大学兽医药理研究室讲师、副教授和硕士生导师。1993.06.-1994.05. 深圳华宝集团股份公司华大兽药有限公司厂长。1994.06.- 华中农业大学畜牧兽医学院教授,博士生导师,国家兽药残留基准实验室(HZAU)、国家兽药安全评价实验室和农业部兽药残留检测重点实验室主任,华中农业大学兽药研究所所长、基础兽医学系主任。目前主持在研的主要科研项目: 1. 畜禽产品中有害物质形成原理与控制途径研究。国家重点基础研究发展计划(973计划,2009CB118800),2009-2013,主持:袁宗辉。2800万元。 2. 有害化合物残留早期鉴定及预警技术研究。农业行业科技专项课题(201203040-3),2012-2016,主持:袁宗辉,220万元。 3. 兽药残留快速检测技术联合研发。国家国际科技合作计划重点项目(国科外字[2012]27号),2012-2014,主持:袁宗辉,400万元

代表性论文收起

  • 1. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring organoarsenic compounds in edible chicken and pork and feed Food Chemistry, v 197, p 821-828, April 15, 2015 2016.01
  • 2. Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells TOXICOLOGICAL SCIENCES 2015.12
  • 3. Metabolism, Distribution, and Elimination of Mequindox in Pigs, Chickens, and Rats JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015.12
  • 4. Two-generation reproduction and teratology studies of feeding aditoprim in Wistar rats JOURNAL OF APPLIED TOXICOLOGY 2015.11
  • 5. Mechanism of adrenocortical toxicity induced by quinocetone and its bidesoxy-quinocetone metabolite in porcine adrenocortical cells in vitro FOOD AND CHEMICAL TOXICOLOGY 2015.11
  • 6. Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies JOURNAL OF APPLIED TOXICOLOGY 2015.10
  • 7. Microbiological toxicity of tilmicosin on human colonic microflora in chemostats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2015.09
  • 8. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for 3-methyl-quinoxaline-2-carboxylic acid in edible animal tissues ANALYTICAL METHODS 2015.09
  • 9. Discovery of the new marker residue of olaquindox in swine, broiler and carp JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2015.07
  • 10. Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle FRONTIERS IN MICROBIOLOGY 2015.07
  • 11. Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015.07
  • 12. Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides (vol 28, pg 470, 2015) CHEMICAL RESEARCH IN TOXICOLOGY 2015.06
  • 13. Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2015.05
  • 14. Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometry FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2015.05
  • 15. Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides CHEMICAL RESEARCH IN TOXICOLOGY 2015.04
  • 16. Metabolism, Distribution, and Elimination of Mequindox in Pigs, Chickens, and Rats Journal of Agricultural and Food Chemistry, v 63, n 44, p 9839-9849, November 11, 2015 2015.01
  • 17. Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats Journal of Agricultural and Food Chemistry, v 63, n 22, p 5557-5569, June 10, 2015 2015.01
  • 18. Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometry Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, v 32, n 5, p 686-701, May 4, 2015 2015.01
  • 19. Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, v 988, p 143-148, April 05, 2015 2015.01
  • 20. Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2014.12
  • 21. Crosstalk of JNK1-STAT3 is critical for RAW264.7 cell survival CELLULAR SIGNALLING 2014.12
  • 22. Tissue Depletion of Quinocetone and Its Five Major Metabolites in Pigs, Broilers, and Carp Fed Quinocetone Premix JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014.11
  • 23. Structure-Function Analysis of Porcine Cytochrome P450 3A29 in the Hydroxylation of T-2 Toxin as Revealed by Docking and Mutagenesis Studies PLOS ONE 2014.10
  • 24. Evaluation of matrix solid-phase dispersion extraction for 11 beta-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry JOURNAL OF SEPARATION SCIENCE 2014.10
  • 25. Biodegradable nanoparticles for intracellular delivery of antimicrobial agents JOURNAL OF CONTROLLED RELEASE 2014.07
  • 26. Benefits and risks of antimicrobial use in food-producing animals FRONTIERS IN MICROBIOLOGY 2014.07
  • 27. Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp FOOD AND CHEMICAL TOXICOLOGY 2014.07
  • 28. Antibiotic alternatives: the substitution of antibiotics in animal husbandry? FRONTIERS IN MICROBIOLOGY?? 2014.06
  • 29. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues FOOD CHEMISTRY 2014.04
  • 30. Evaluation of matrix solid-phase dispersion (MSPD) extraction for multi-fenicols determination in shrimp and fish by liquid chromatography-electrospray ionisation tandem mass spectrometry FOOD CHEMISTRY 2014.01
  • 31. Metabolism, Distribution, and Excretion of Deoxynivalenol with Combined Techniques of Radiotracing, High-Performance Liquid Chromatography Ion Trap Time-of-Flight Mass Spectrometry, and Online Radiometric Detection JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014.01
  • 32. High Risk of Embryo-Fetal Toxicity: Placental Transfer of T-2 Toxin and Its Major Metabolite HT-2 Toxin in BeWo Cells TOXICOLOGICAL SCIENCES 2014.01
  • 33. A physiologically based pharmacokinetic model for the prediction of the depletion of methyl-3-quinoxaline-2-carboxylic acid, the marker residue of olaquindox, in the edible tissues of pigs JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2014.01
  • 34. Evaluation of matrix solid-phase dispersion extraction for 11 β-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry Journal of Separation Science, v 37, n 18, p 2574-2582, 2014 2014.01
  • 35. Metabolism, distribution, and excretion of deoxynivalenol with combined techniques of radiotracing, high-performance liquid chromatography ion trap time-of-flight mass spectrometry, and online radiometric detection Journal of Agricultural and Food Chemistry 2014.01
  • 36. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues Food Chemistry 2014.01
  • 37. Biodegradable nanoparticles for intracellular delivery of antimicrobial agents Journal of Controlled Release 2014.01
  • 38. Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods Analytical and Bioanalytical Chemistry 2014.01
  • 39. Evaluation of matrix solid-phase dispersion extraction for 11 β-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry Journal of Separation Science 2014.01
  • 40. Tissue depletion of quinocetone and its five major metabolites in pigs, broilers, and carp fed quinocetone premix Journal of Agricultural and Food Chemistry 2014.01
  • 41. Mechanism of Porcine Liver Xanthine Oxidoreductase Mediated N-Oxide Reduction of Cyadox as Revealed by Docking and Mutagenesis Studies PLOS ONE 2013.12
  • 42. Impact of cyadox on human colonic microflora in chemostatmodelsle REGULATORY TOXICOLOGY AND PHARMACOLOGY 2013.12
  • 43. Development of a direct ELISA based on carboxy-terminal of penicillin-binding protein BlaR for the detection of beta-lactam antibiotics in foods ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2013.11
  • 44. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction method for the simultaneous determination of sudan dyes and their metabolites in the edible tissues and eggs of food-producing animals JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2013.11
  • 45. Antibacterial action of quinolones: From target to network EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2013.09
  • 46. Trichothecenes: Structure-Toxic Activity Relationships CURRENT DRUG METABOLISM 2013.07
  • 47. Genotoxicity evaluation of Mequindox in different short-term tests FOOD AND CHEMICAL TOXICOLOGY 2013.03
  • 48. Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo FOOD AND CHEMICAL TOXICOLOGY 2013.01
  • 49. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction and auto solid-phase clean-up method for the determination of Fusarium toxins in animal derived foods JOURNAL OF CHROMATOGRAPHY A 2013.01
  • 50. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction method for the simultaneous determination of sudan dyes and their metabolites in the edible tissues and eggs of food-producing animals Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2013.01
  • 51. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction and auto solid-phase clean-up method for the determination of Fusarium toxins in animal derived foods Journal of Chromatography A 2013.01
  • 52. Development of a direct ELISA based on carboxy-terminal of penicillin-binding protein BlaR for the detection of β-lactam antibiotics in foods Analytical and Bioanalytical Chemistry 2013.01
  • 53. Evaluation of matrix solid-phase dispersion (MSPD) extraction for multi-fenicols determination in shrimp and fish by liquid chromatography- electrospray ionisation tandem mass spectrometry Food Chemistry 2013.01
  • 54. Development of a sensitive and robust liquid chromatography coupled with tandem mass spectrometry and a pressurized liquid extraction for the determination of aflatoxins and ochratoxin A in animal derived foods :JournalofChromatographyA 2012.01
  • 55. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs Journal of Agricultural and Food Chemistry 2012.01
  • 56. Development of an accelerated solvent extraction, ultrasonic derivatisation LC-MS/MS method for the determination of the marker residues of nitrofurans in freshwater fish Food Additives and Contaminants - Part A Chemistry, Analysis,Control, Exposure and Risk Assessment 2012.01
  • 57. Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2012.01
  • 58. Simultaneous determination of 15 aminoglycoside(s) residues in animal derived foods by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry Food Chemistry 2012.01
  • 59. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2012.01
  • 60. Development of a sensitive and robust liquid chromatography coupled with tandem mass spectrometry and a pressurized liquid extraction for the determination of aflatoxins and ochratoxin A in animal derived foods JOURNAL OF CHROMATOGRAPHY A 2012.01
  • 61. In Vitro Development and Transfer of Resistance to Chlortetracycline in Bacillus subtilis JOURNAL OF MICROBIOLOGY 2012.01
  • 62. Development of Quinoxaline 1, 4-Dioxides Resistance in Escherichia coli and Molecular Change under Resistance Selection PLOS ONE 2012.01
  • 63. Key genetic elements and regulation systems in methicillin-resistant Staphylococcus aureus FUTURE MICROBIOLOGY 2012.01
  • 64. Inhibitors targeting on cell wall biosynthesis pathway of MRSA MOLECULAR BIOSYSTEMS 2012.01
  • 65. Development and Validation of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for the Screening of Tylosin and Tilmicosin in Muscle, Liver, Milk, Honey and Eggs JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012.01
  • 66. Simultaneous determination of 15 aminoglycoside(s) residues in animal derived foods by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry FOOD CHEMISTRY 2012.01
  • 67. Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2012.01
  • 68. Development of an accelerated solvent extraction, ultrasonic derivatisation LC-MS/MS method for the determination of the marker residues of nitrofurans in freshwater fish FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2012.01
  • 69. JAK/STAT Pathway Plays a Critical Role in the Proinflammatory Gene Expression and Apoptosis of RAW264.7 Cells Induced by Trichothecenes as DON and T-2 Toxin TOXICOLOGICAL SCIENCES 2012.01
  • 70. Two generation reproduction and teratogenicity studies of feeding quinocetone fed to Wistar rats FOOD AND CHEMICAL TOXICOLOGY 2012.01
  • 71. Pharmacokinetics of tulathromycin and its metabolite in swine administered with an intravenous bolus injection and a single gavage JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2012.01
  • 72. mRNA expression profiles of P450 3A enzymes in the liver and small intestine of the domestic pig RESEARCH IN VETERINARY SCIENCE?? 2012.01
  • 73. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2012.01
  • 74. The Role of RamA on the Development of Ciprofloxacin Resistance in Salmonella enterica Serovar Typhimurium PLOS ONE 2011.01
  • 75. Metabolic Pathways of Ochratoxin A CURRENT DRUG METABOLISM 2011.01
  • 76. The metabolism of olaquindox in rats, chickens and pigs TOXICOLOGY LETTERS 2011.01
  • 77. Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats TOXICOLOGY AND APPLIED PHARMACOLOGY 2011.01
  • 78. In vitro biotransformation and investigation of metabolic enzymes possibly responsible for the metabolism of bisdesoxyolaquindox in the liver fractions of rats, chicken, and pigs TOXICOLOGY 2011.01
  • 79. Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox TOXICOLOGY 2011.01
  • 80. The physiologic and phenotypic alterations due to macrolide exposure in Campylobacter jejuni INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY 2011.01
  • 81. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction method for the determination of benzimidazole residues in edible tissues JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
  • 82. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
  • 83. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction for determination of glucocorticoid residues in edible tissues JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
  • 84. Development of a high-performance liquid chromatography method for the simultaneous quantification of four organoarsenic compounds in the feeds of swine and chicken JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
  • 85. Determination of sodium nifurstyrenate and nitrovin residues in edible food by liquid chromatography-tandem mass spectrometry after ultrasound-assisted extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
  • 86. Identification of carbadox metabolites formed by liver microsomes from rats, pigs and chickens using high-performance liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2011.01
  • 87. Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2011.01
  • 88. A comparison of hepatic in vitro metabolism of T-2 toxin in rats, pigs, chickens, and carp XENOBIOTICA 2011.01
  • 89. Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats FOOD AND CHEMICAL TOXICOLOGY 2011.01
  • 90. Simultaneous determination of malachite green, gentian violet and their leuco-metabolites in shrimp and salmon by liquid chromatography-tandem mass spectrometry with accelerated solvent extraction and auto solid-phase clean-up FOOD CONTROL 2011.01
  • 91. Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni MICROBIAL PATHOGENESIS 2011.01
  • 92. Simultaneous determination of lincomycin and spectinomycin residues in animal tissues by gas chromatography-nitrogen phosphorus detection and gas chromatography-mass spectrometry with accelerated solvent extraction FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2011.01
  • 93. Development and validation on indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2011.01
  • 94. Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4 BIOSCIENCE REPORTS 2011.01
  • 95. Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2011.01
  • 96. A chronic toxicity study of cyadox in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2011.01
  • 97. Inhibition of cytochrome P450 2A participating in coumarin 7-hydroxylation in pig liver microsomes JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2011.01
  • 98. Analytical determination and pharmacokinetics of major metabolites of carbasalate calcium in broilers following oral administration JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2011.01
  • 99. Development of a high-performance liquid chromatography method for the simultaneous quantification of four organoarsenic compounds in the feeds of swine and chicken Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
  • 100. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction method for the determination of benzimidazole residues in edible tissues Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
  • 101. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction for determination of glucocorticoid residues in edible tissues ournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
  • 102. Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine, chicken and bovine with accelerated solvent extraction Food Chemistry 2011.01
  • 103. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
  • 104. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment Abbreviated source title:Food Addit. Contam. Part A Chem. Anal. Control Exposure Risk Assess. 2011.01
  • 105. Metabolic pathways of trichothecenes DRUG METABOLISM REVIEWS 2010.01
  • 106. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
  • 107. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with pressurized liquid extraction for simultaneous quantification and confirmation of cyromazine, melamine and its metabolites in foods of animal origin ANALYTICA CHIMICA ACTA 2010.01
  • 108. The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken TOXICOLOGY LETTERS 2010.01
  • 109. Interactions of NADPH oxidase, renin-angiotensin-aldosterone system and reactive oxygen species in mequindox-mediated aldosterone secretion in Wistar rats TOXICOLOGY LETTERS 2010.01
  • 110. Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2010.01
  • 111. Long-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male rats TOXICOLOGY LETTERS 2010.01
  • 112. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals ANALYTICA CHIMICA ACTA 2010.01
  • 113. Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine, chicken and bovine with accelerated solvent extraction FOOD CHEMISTRY 2010.01
  • 114. Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2010.01
  • 115. Development of a high-performance liquid chromatography method to monitor the residues of benzimidazoles in bovine milk JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2010.01
  • 116. Metabolism of mequindox in liver microsomes of rats, chicken and pigs RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2010.01
  • 117. Residue Depletion and Tissue-Plasma Correlation of Methyl-3-quinoxaline-2-carboxylic Acid after Dietary Administration of Olaquindox in Pigs JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010.01
  • 118. Tissue Depletion and Concentration Correlations between Edible Tissues and Biological Fluids of 3-Amino-2-oxazolidinone in Pigs Fed with a Furazolidone-Medicated Feed JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010.01
  • 119. ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro CHEMICO-BIOLOGICAL INTERACTIONS 2010.01
  • 120. Quantification of Mutated Alleles of 23S rRNA in Macrolide-Resistant Campylobacter by TaqMan Real-Time Polymerase Chain Reaction FOODBORNE PATHOGENS AND DISEASE 2010.01
  • 121. Acute and subchronic toxicological evaluation of Mequindox in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2010.01
  • 122. Population pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in chicken based on retrospective data, incorporating first-pass metabolism Journal of Veterinary Pharmacoogy and Therapeutics 2010.01
  • 123. Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of glucocorticoid residues in edible tissues of swine, cattle, sheep, and chicken FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2010.01
  • 124. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
  • 125. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
  • 126. Determination of sodium nifurstyrenate and nitrovin residues in edible food by liquid chromatography-tandem mass spectrometry after ultrasound-assisted extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
  • 127. Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
  • 128. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with pressurized liquid extraction for simultaneous quantification and confirmation of cyromazine, melamine and its metabolites in foods of animal origin Analytica Chimica Acta 2010.01
  • 129. Development of a high-performance liquid chromatography method to monitor the residues of benzimidazoles in bovine milk Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
  • 130. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals Analytica Chimica Acta 2010.01
  • 131. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals Analytica Chimica Acta 2010.01
  • 132. Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro Analytical and Bioanalytical Chemistry 2010.01

指导研究生优秀论文 收起

  • 1. 猪沙门菌对恩诺沙星耐药判定标准研究 校优论文 潘华芳 2014
  • 2. T-2毒素的代谢和毒作用信号转导研究 校优论文 吴庆华 2014
  • 3. β-内酰胺类抗生素受体的筛选及ELISA试剂盒研制 校优论文 彭娟 2014
  • 4. 多重耐药泵及其调控蛋白在鼠伤寒沙门氏菌对氟喹诺酮类耐药中的作用 校优论文 孙亚伟 2012
  • 5. 动物性食品中兽药残留定量和确证分析关键技术研究 校优论文 陈冬梅 2011
  • 6. 乙酰甲喹临床毒理学研究 校优论文 AWAIS IHSAN 2011
  • 7. 动物源食品中兽药残留多组分定量/确证方法的关键技术研究 校优论文 陶燕飞 2011
  • 8. 动物可食性组织中兽药多残留检测关键技术研究 校优论文 余欢 2011
  • 9. 喹噁啉类在大鼠、猪和鸡的比较代谢研究 国优提名 刘兆颖 2011
  • 10. 弯曲杆菌对大环内酯类的耐药发生与适应性研究 校优论文 郝海红 2010
  • 11. 呋喃唑酮在猪体内生理药动学模型研究 校优论文 刘宇 2010
  • 12. 喹噁啉类在大鼠、猪和鸡的比较代谢研究 省优论文 刘兆颖 2010
  • 13. 喹赛多生产过程中的三废处理技术研究 校优论文 邱荣超 2009
  • 14. 喹噁啉类在大鼠、猪和鸡的比较代谢研究 校优论文 刘兆颖 2009
  • 15. 论文题目:喹噁啉类定量分析方法及脱氧速率研究 校优论文 吴玉杰 2008
  • 16. 动物性食品中氯苯胍和左旋咪唑残留检测方法研究 校优论文 曾勇 2008

教学情况 收起

  • 1. 兽医药理学A*
  • 2. 兽医药理学B
  • 3. 兽医药理学A

科研项目 收起

  • 1. 牛脂肪中头孢氨苄的残留检测方法及牛组织(肌肉、脂肪、肝脏、肾脏)中卡那霉素A的残留检测方法 2017.04
  • 2. 美洛昔康残留检测方法验证复核 2017.03
  • 3. 武汉市动物性食品残留检测工程技术研究中心考核奖励 2016.10
  • 4. 新兽药研发合作协议-乙酰吉他霉素在猪临床前试验(二期) 2016.01
  • 5. 制定《畜禽肝脏、肾脏等主要可食组织中12类150种混合化学污染物同步检测-液相色谱-高分辨率质谱方法》标准 2016.01
  • 6. 整合制定《动物性食品中喹乙醇及代谢物残留量的测定 高效液相色谱法(或液相色谱-串联质谱法)》标准 2016.01
  • 7. 修订《奶和奶粉中青霉素类药物多残留的测定 液相色谱-串联质谱法》标准(GB/T 22975-2008) 2016.01
  • 8. 《动物性食品中大观霉素残留量的测定 气相色谱-质谱法》标准验证与审定(GB 29685-2013)(2015延续项目) 2016.01
  • 9. 《动物性食品中氨基糖苷类药物多残留的测定 液相色谱-串联质谱法》标准验证与审定(GB/T 21323-2007)(2015年延续项目) 2016.01
  • 10. 《动物性食品中青霉素类药物多残留的测定 液相色谱-串联质谱法》标准验证与审定(GB/T 20755-2006、GB/T 21315-2007)(2015年延续项目) 2016.01
  • 11. 农产品质量安全监管专项(风险评估) 2016.01
  • 12. 高风险兽药安全试验及风险评估 2016.01
  • 13. 兽药残留检测方法标准研究制定 2015.01
  • 14. 喹乙醇风险评估与风险因子跟踪调查 2015.01
  • 15. 农业部畜禽产品质量安全风险评估实验室 2015.01
  • 16. 湖北省高端人才引领培养计划(第一层次) 2014.01
  • 17. 湖北省高端人才引领培养计划(第一层次) 2014.01
  • 18. 畜禽产品兽药残留预警技术引进合作 2014.01
  • 19. 试剂盒复核试验费 2014.01
  • 20. 试剂盒复核试验费 2014.01
  • 21. 阿莫西林克拉维酸钾注射液项目开发 2014.01
  • 22. 试剂盒复核试验费 2014.01
  • 23. 制定动物性食品中喹烯酮残留限量 2013.03
  • 24. 试剂盒复核试验费 2013.01
  • 25. 试剂盒复核试验费 2013.01
  • 26. 试剂盒复核试验费 2013.01
  • 27. 试剂盒复核试验费 2013.01
  • 28. 试剂盒复核试验费 2013.01
  • 29. 试剂盒复核试验费 2013.01
  • 30. 试剂盒复核试验费 2013.01
  • 31. 潮霉素B预混剂项目开发 2013.01
  • 32. 加米霉素注射液项目委托试验研究 2013.01
  • 33. 乙酰吉他霉素在猪临床前的试验 2013.01
  • 34. 试剂盒复核试验费 2013.01
  • 35. 开展高风险性兽药安全性评价及风险评估、兽药休药期试验及制定工作 2012.05
  • 36. 兽药残留快速检测技术联合研发 2012.01
  • 37. 喹噁啉类兽药安全试验及风险评估1 2012.01
  • 38. 试剂盒复核试验费 2012.01
  • 39. 试剂盒复核试验费 2012.01
  • 40. 试剂盒复核试验费 2012.01
  • 41. 试剂盒复核试验费 2012.01
  • 42. 试剂盒复核试验费 2012.01
  • 43. 试剂盒复核试验费 2012.01
  • 44. 试剂盒复核试验费 2012.01
  • 45. 试剂盒复核试验费 2012.01
  • 46. 磺胺甲基异恶唑(SMZ)-甲氧苄定(TMP)复方混悬剂(国家四类新兽药)在鸡的临床试验 2012.01
  • 47. 试剂盒复核试验费 2012.01
  • 48. 卡巴匹林钙可溶性粉项目委托试验研究协议 2012.01
  • 49. 试剂盒复核试验费 2012.01
  • 50. 试剂盒复核试验费 2012.01
  • 51. 试剂盒复核试验费 2012.01
  • 52. 试剂盒复核试验费 2012.01
  • 53. 杆菌肽锌在猪残留消除试验 2012.01
  • 54. 研发协议 2012.01
  • 55. 兽药残留检测国家重点实验室(A类) 2011.08
  • 56. 动物源食品中抗菌药残留微生物学高通量筛选技术改进与产业化研究 2011.05
  • 57. 农业部食品安全评价重点开放实验室 2011.01
  • 58. 国家兽药残留基准实验室(华中农业大学) 2011.01
  • 59. 试剂盒复核试验费 2011.01
  • 60. 试剂盒复核试验费 2011.01
  • 61. 氯霉素快速检测金标试纸板复核试验报告 2011.01
  • 62. 呋喃唑酮代谢物酶联免疫试剂盒复核试验费 2011.01
  • 63. 试剂盒复核试验费 2011.01
  • 64. 试剂盒复核试验费 2011.01
  • 65. 试剂盒复核试验费 2011.01
  • 66. 试剂盒复核试验费 2011.01
  • 67. 试剂盒复核试验费 2011.01
  • 68. 试剂盒复核试验费 2011.01
  • 69. 试剂盒复核试验费 2011.01
  • 70. 试剂盒复核试验费 2011.01
  • 71. 银杏内酯B药动学样品检测 2011.01
  • 72. 试剂盒复核试验费 2011.01
  • 73. 试剂盒复核试验费 2011.01
  • 74. 动物性食品中锥虫胂胺残留量的测定 液相色谱-串联质谱法 2010.05
  • 75. 动物性食品中吉他霉素残留量的测定 高效液相色谱法 2010.05
  • 76. 动物性食品中红霉素残留量的测定 高效液相色谱法 2010.05
  • 77. 水产品中双甲脒残留量的测定 气相色谱-质谱法 2010.05
  • 78. 抗菌剂耐药性安全评价及耐药性监测及技术标准制定 2010.01
  • 79. 莱克多巴胺等高风险兽药残留检测方法研究、安全监测、残留消除规律试验及相关试验、评估工作 2010.01
  • 80. 莱克多巴胺等高风险兽药残留检测方法研究、安全监测、残留消除规律试验 2010.01
  • 81. 动物源性食品中兽药残留检测技术培训 2010.01
  • 82. 动物性食品中兽药残留最高限量标准 2009.12
  • 83. 动物性食品中双甲脒残留量的测定 液相色谱-串联质谱法 2009.10
  • 84. 动物性食品中9种青霉素类药物残留量的测定 液相色谱-串联质谱法 2009.10
  • 85. 动物性食品中11种氨基苷类药物残留量的测定 液相色谱-串联质谱法 2009.10
  • 86. 动物源食品中壮观霉素和林可霉素残留的测定 高效液相色谱法 2009.10
  • 87. 动物性食品中吡啶基醋酸汞和醋酸汞残留量的测定 原子荧光法 2009.10
  • 88. 动物性食品中聚醚类药物残留量的测定 高效液相色谱法 2009.10
  • 89. 动物性食品中吡利霉素残留量的测定 高效液相色谱法 2009.10
  • 90. 我国兽用处方药确定原则及清单的制定 2009.01
  • 91. 畜禽产品中有害物质形成原理与控制途径研究 2009.01
  • 92. 农产品质量安全风险评估
  • 93. 开展高风险兽药安全性试验及风险评估、兽药休药期试验及制定工作
  • 94. 兽药残留新型检测技术国际合作与交流
  • 95. 兽药残留及动物源病原菌耐药性控制技术研究
  • 96. 油料玉米生物毒素摸底排查评估
  • 97. 制定喹烯酮在猪中的最大残留限量标准
  • 98. 修订《动物性食品及蜂蜜中双甲脒残留量的测定气相色谱-质谱法》标准
  • 99. 修订《动物性食品中糖皮质激素类药物残留量的测定液相色谱-串联质谱法》标准

专利成果 收起

社会服务 收起

招收研究生专业 收起

  • 1. 基础兽医学
  • 2. 兽医
  • 3. 食品科学
  • 4. 农产品加工及贮藏工程

其他 收起

科研成果及奖励 获奖成果 1. 袁宗辉。动物可食性组织中兽药残留系列分析方法研究。湖北省归国华侨联合会科技奖励基金三等奖,2011 2. 袁宗辉、陈冬梅、陶燕飞、王玉莲、刘振利、彭大鹏、黄玲利、戴梦红、黄华、路勇、班付国、宋志超、贾振民、林永。动物源性食品中糖皮质类药物残留检测液相色谱-串联质谱法。湖北省标准创新贡献奖一等奖,湖北省技术监督局,2010。 3. 袁宗辉,王玉莲,陶燕飞,陈冬梅,彭大鹏,黄玲利,伍金娥,于刚,余欢,刘振果,吴玉杰,常超,叶胜强,张泽英,赵春保,刘振利,范盛先。兽药残留检测关键技术创新与配套集成研发。高等学校科学研究优秀成果奖科学技术进步奖一等奖,2008。 4. 袁宗辉,陶燕飞,陈冬梅,王玉莲,黄玲利,王大菊,范盛先,于刚,余欢,吴玉杰。动物可食性组织中兽药残留系列分析方法研究。湖北省科技进步二等奖,2008。 5. 袁宗辉,缪小群、尹烨华、冯淇辉、曾振灵。传染病对兽用抗菌药物动力学的影响研究。教育部科技进步奖三等奖,1998。 6. 家畜抗菌药物代谢动力学研究,国家教委科技进步奖(甲类)三等奖,1993。 另外,鉴定成果13项,其中国际领先水平8项,国际先进水平5项。申报国家发明专利47项,获得授权23项。备案兽药残留检测试剂盒产品17种,制订国家标准40余种,制备标准物质近20种。 国家973项目首席科学家,食品安全国家标准审评委员会委员,国家农产品质量安全风险评估专家委员会委员,中国国际食品法典委员会(CAC)农业专家工作组成员,中国兽药典委员会委员,全国兽药残留专家委员会委员,农业部农产品质量安全专家组专家,农业部兽药审评委员会委员,湖 主编专著3部,参编8部,审校书稿3部。是国家973计划首席专家,农业部中青年有突出贡献专家、国务院特殊津贴专家、 教育部跨世纪优秀人才培养计划基金获得者、湖北省新世纪高层次人才工程人选、 湖北省跨世纪学科带头人、湖北省跨世纪111人才工程首批人选。